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bioMérieux collaborated with the French Agency for Food, Environmental, and Occupational Health & Safety


Numerous food industries including the raw cheese, beef, and produce industries have long been plagued by poor EHEC (enterohemorrhagic E. coli) detection solutions. Traditional PCR-based EHEC screens have high unconfirmed positive rates due to the presence of non-EHEC competing organisms that also have eae and stx genes. As a result, some food products see a 15-20% incidence rate of EHEC natural contamination. 

bioMérieux researchers collaborated with the French Agency for Food, Environmental, and Occupational Health & Safety (ANSES) and using Predictive Diagnostics, analyzed over 10-years of research to solve this problem. The results confirmed the existence of two additional biomarkers, that when analyzed alongside eae and stx genes proved to increase the accuracy of detection significantly.

These findings can be leveraged for a significant impact on the raw cheese, beef, and produce industries. Download the full PDF for more details, or contact a bioMérieux representative today.

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Key Takeaways

  • New research has the potential to eliminate the unconfirmed positive dilemma of traditional PCR EHEC screens.
  • Two additional biomarkers, espV and espK have been found to co-locate with eae/stx.
  • The combined analysis of all four genes, compared against confirmed clinical and food sequences, increased the accuracy of detection significantly.

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As leaders in microbiology testing for over 55 years, bioMérieux offers rapid and traditional microbiology solutions for manufacturers. From sample preparation to quality testing to pathogen detection and identification, bioMérieux has a diagnostic solutions that will allow a quick and confident release of products.

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